Open Access Open Access  Restricted Access Subscription or Fee Access

In Vivo Hepatoprotective Effect of the Trianthema Decandra

G. Priya, Dr. C. Chellaram


In the present investigation, an attempt has been made to test the hepatoprotective efficacy of the herbal plant Trianthema decandra on carbon tetrachloride induced toxic hepatitis. The carbon tetrachloride induced rats showed increased activity of Total protein, Total cholesterol, Triglycerides, ALP, AST, ALT and bilirubin in serum. The herbal Trianthema decandra leaf extract treated rats showed marked reduction in the activity of TP, TC, TG, ALP, AST, ALT &Bilirubin when compared with normal rats.


Trianthema decandra,Trianthema portulacastrum,T. decandra

Full Text:



Lieber, C.S. 1991. Journal of American College Nutrients, 10: 602-609.

Mehandale, H. M, Roth, R.A, Gandolfi, A.J, Klaunig, J.E, Le-Master. J.J and Curtis LR. 1986. Novel Mechanism in chemically induced hepatotoxicity. FASEB J. 104: 826-829.

Melloy, H. T and Evelyn, K. A. 1937. The determination of bilirubin with the photoelectric colorimeter. J. Biol. chem. 119:481-490.

Paduraru, I, Saramet, A, Danila G.H, Nichiform, J and Lacobovici A. 1996. Antioxidant action of a new flavonic derivative in acute CCL4 intoxication. Eur. J. Drug metab. Phamacokinetic, 21:1-6.

Recknagle, R.O, Glende, E.A Jr, Dolak, J.A and Walker, R.L. 1989. Mechanism of CCL4 toxicity Pharmacol. Ther. 43: 139-54.

Reitman, S and Frankel, S. 1957. A Colorimetric method for the determination of glutamic pyruvic transaminases. Am. j. clinic. pathol. 28:56-63.

Seef, L.B and Adlee. 1986. Acetaminophen hepatotoxicity in alcoholics: A Therapeutic Misadventure. An Intern Med. 104: 399-404.

Sharma, A., Chakraborti, K.K and Handa, S. S.. 1991. Anti-hepatotoxic activity of some Indian herbal formulations as compared to silymarin”. Fitoterpia. 62:229-235.

Thakur C.B, Dixit, V.K. and Sarat, S.. 1991, Hepatoprotective activity of Asteracantha longifolia Indian Drugs, 28 (9):400-402

Visen,P.K.S, Shukla, B, Patnaik, G.K and Dhawan, B.N. 1993. Prevention of Galactosamine induced hepatic damage by picroliv: study on bile low and isolated hepatocytes (exvivo) Planta Med.59:37-41.

Wolf, P.L. 1999. Biochemical diagnosis of liver disease Indian. J. Clinical Biochem. 14:59-65.


  • There are currently no refbacks.

Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.