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Prediction of Secondary Structure of using Neural Networks and Machine Learning Techniques

Dr. K. Meena, M. Manimekalai

Abstract


One of the most significant problems in biomedical
research today is the prediction of protein structure from knowledge of the primary amino acid sequence. Secondary Structure Prediction (SSP) is a very typical problem in the field of bioinformatics.Prediction of secondary structure of Proteins can be done from theProtein sequence. In the Protein structure prediction, the Amino Acid sequence of a Protein, the so-called primary structure, can be easily determined from the sequence on the Gene that codes for it. This primary structure exclusively determines a structure in its native environment. Thus primary structure plays a key role in understanding the function of the Protein. Majority of the previous research have ignored the influence of residue conformational preference on structure prediction of proteins. The primary focus of
this research is to investigate a variety of approaches for employing ANN and Machine Learning techniques in order to predict the secondary structure of proteins in soybeans.


Keywords


Protein Structure Prediction, RBFNN, MELM, SVM, Amino Acid, Soybeans

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