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Real Time, Non-invasive Cerebral Blood Oxygenation Monitoring Device

S. Anita Rashmi Priscilla, K. Kevin Keerthi Prakash, Dr.S.V. Senthilnathan, S. Gnanavel

Abstract


This paper describes the design of a simple, low-cost microcontroller based cerebral blood oxygenation monitoring device. This device is based on a non-invasive sensor that detects the blood oxygenation related to brain function. It is a reflectance based sensor which consists of IR emitter of wavelength 940 nm and ultrared LED 660nm and a detector. By measuring returned light at from the light source, the hemoglobin oxygen saturation in frontal cortex can be determined. Oxygen saturation is an indicator of oxygen transport in the body. Cerebral or regional oxygen saturation [1] is commonly termed as rSO2. There are different methods to monitor cerebral blood flow. One of them which has been recently introduced is measurement of cerebral oxygen saturation (rSO2) with cerebral oximetry, which is noninvasive [9] and easy to use. Since it measures mostly venous blood oxygen saturation and does not require pulsatile signal, it can be used as a measure of global perfusion during cardiac surgery [1].

Keywords


Haemoglobin, Reflectance, rSO2, Venous Blood

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References


Yichao Teng, Haishu Ding, Qingcheng Gong Biomedical Engineering Department, School of Medicine, Tsinghua University, Beijing 100084, China Non-invasive monitoring of human cerebral oxygen saturation by near infrared spectroscopy: Instrumentation, calibration and application in cardiopulmonary bypass (2005).

Hewlett Packard Journal, A new family of sensors vol 42, no.4, pg 39-53 February (1997).

Camilo povea et al. “Effects of Intermittent Hypoxia on Heart Rate Variability during Rest and Exercise”. High altitude medicine & biology, Volume 6, Number 3, pp 215-225, 2005.

Christian Gutierrez, Shane Smoleny, Malcolm Heimer, Iker Yaylali (Biomedical Engineering Institute, Florida International University, Miami.Non-Invasive Functional Mapping of the Brain Using Cerebral Oximeter (2002).

Daniel J. Ford, Deanna R. Nachreiner, “Design of a Pulse Oximeter for Use in Mice”, 2006.

Damianou and J A Crowe. “The wavelength dependence of pulse oximetry” (1990).

Guyton and Hall,(2008) “Text book of medical physiology”, Elsevier publication.pp.502 – 511 & 537 -544.

Gupta, S.S Ahluwalia & SS Randhawa “Design and development of Pulse Oximeter”. CSIO. Chandigarh, (1995).

Hayes and E.B. Merrick, “Continuous, Non-Invasive Measurements of Blood Oxygen Levels,” Hewlett-Packard Journal, Vol. 28, no. 2, pp. 2-10, October 1976.K. (1996).

Justin P. Phillips et al. (2009),”Measurements of Cerebral Arterial Oxygen Saturation using a Fiber-optic Pulse Oximeter”.IEEE transactions.

Kelvin KT, Steven J.B “Pulse Oximetry", Anaesthesiology, vol 70, No. 1, pp 98-108, Jan. (1989).

Mayer and Dietmar Miller, “A New Family of Sensors for Pulse Oximetry”, (2004).

MendeIson Y, Kent J.C "Variation in optical absorption spectra of adult and fetal haemoglobin and its effect on Pulse Oximetry". IEEE Trans Biomed Eng, pp 844-8413, (1981).

Sohrab Negargar, Ata Mahmoudpour, Reza Taheri, Sarvin Sanaie “The relationship between cerebral oxygen saturation changes and Post operative neurologic complications in patients undergoing cardiac surgery”, Pakistan journal of medical sciences, published by Professional medical publications, Vol.23, no.3, April-June (2007).

W. S. Johnston, and Y. Mendelson Investigation of Signal Processing Algorithms for an Embedded Microcontroller-Based Wearable Pulse Oximeter (2006).

Concise medical physiology, by Sujit K.Chaudhuri, second edition Chapter IV.5 Carriage of O2 by the blood and their exchange, pg.168-169 second edition (1993).

David C Klonoff, MD, FRCP “Non-invasive Blood Glucose Monitoring” Department of Medicine, University of California at San Francisco (October 1996).




DOI: http://dx.doi.org/10.36039/AA072012013

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